• News From The Journal Of Clinical Investigation: May 15, 2012 News From The Journal Of Clinical Investigation: May 15, 2012 DEVELOPMENT Hope for new treatment options for the rare disease Beare-Stevenson syndrome Beare-Stevenson cutis gyrata syndrome is an extremely rare genetic disease that causes serious physical problems affecting the skin and skull...
  
  Created on: 16 May 2012 | 1:00 am
  
  16 May 2012 | 1:00 am
• Discovery Of New Gene Mutations Leads To Breakthrough In Understanding The Cause Of Bile Duct Cancer Discovery Of New Gene Mutations Leads To Breakthrough In Understanding The Cause Of Bile Duct Cancer A team of international scientists has made a significant breakthrough in understanding the cause of bile duct cancer, a deadly type of liver cancer. By identifying several new genes frequently mutated in bile duct cancers, researchers are paving the way[…]
  
  Created on: 16 May 2012 | 12:00 am
  
  16 May 2012 | 12:00 am
• Mouse Model Reveals Scarring Cells Revert To Inactive State As Liver Heals Mouse Model Reveals Scarring Cells Revert To Inactive State As Liver Heals An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, report that significant numbers of myofibroblasts - cells that produce the fibrous scarring in chronic liver injury - revert to an inactive[…]
  
  Created on: 9 May 2012 | 1:00 am
  
  9 May 2012 | 1:00 am
• Good News And Bad News In Fatty Liver Disease And Diabetes Good News And Bad News In Fatty Liver Disease And Diabetes A Penn research team, led by Mitchell Lazar, MD, PhD, director of the Institute for Diabetes, Obesity, and Metabolism at the Perelman School of Medicine, University of Pennsylvania, reports in Nature Medicine that mice in which an enzyme called histone[…]
  
  Created on: 8 May 2012 | 1:00 am
  
  8 May 2012 | 1:00 am
• Comorbidities Increase Risk Of Mortality In COPD Patients Comorbidities Increase Risk Of Mortality In COPD Patients A new study published online in the American Journal of Respiratory and Critical Care Medicine reveals that comorbidities amongst patients with chronic obstructive pulmonary disease (COPD) are common, and that several of these comorbidities are independently linked to a higher[…]
  
  Created on: 4 May 2012 | 3:00 pm
  
  4 May 2012 | 3:00 pm
• Growth Of Hepatocellular Carcinoma Halted By Combining Two MTOR Inhibitors Growth Of Hepatocellular Carcinoma Halted By Combining Two MTOR Inhibitors The combination of two inhibitors of protein mTOR stops the growth of primary liver cancer and destroys tumour cells, according to a study by researchers of the Group of Metabolism and Cancer at Bellvitge Biomedical Research Institute (IDIBELL). The study[…]
  
  Created on: 4 May 2012 | 1:00 am
  
  4 May 2012 | 1:00 am
• Cellular Energy May Be Depleted In Patients With Obesity And Diabetes By Increased Fructose Consumption Cellular Energy May Be Depleted In Patients With Obesity And Diabetes By Increased Fructose Consumption Obese people who consume increased amounts of fructose, a type of sugar that is found in particular in soft drinks and fruit juices, are at risk for nonalcoholic fatty liver disease (NFALD) and more its more severe forms, fatty inflammation[…]
  
  Created on: 4 May 2012 | 12:00 am
  
  4 May 2012 | 12:00 am
• Interferon For Hepatitis C Can Cause Depression Interferon For Hepatitis C Can Cause Depression There's a high rate of depression among patients with hepatitis C, but a standard treatment for the disease includes a drug, interferon, that can cause depression. In a review article, researchers tackle the complexities of diagnosing and managing depression before[…]
  
  Created on: 2 May 2012 | 5:00 am
  
  2 May 2012 | 5:00 am
• No Increase In Mortality Rates For Liver Transplants Performed At Night And Weekends No Increase In Mortality Rates For Liver Transplants Performed At Night And Weekends A new study, funded in part by a grant from the National Institutes of Health (NIH), shows that liver transplants performed at night or on weekends do not adversely affect patient or graft survival...
  
  Created on: 30 Apr 2012 | 12:00 am
  
  30 Apr 2012 | 12:00 am
• FDA Update Safety Information On HIV Drug Victrelis (Boceprevir) FDA Update Safety Information On HIV Drug Victrelis (Boceprevir) The United States Food and Drug Administration (FDA) is updating information on Victrelis (boceprevir). The drug is used as a hepatitis C (HCV) protease inhibitor. It is combined with various ritonavir-boosted human immunodeficiency virus (HIV) protease inhibitors...
  
  Created on: 27 Apr 2012 | 2:00 pm
  
  27 Apr 2012 | 2:00 pm
• 70-Fold Elevated Risk Of Hepatocellular Carcinoma In Those With Family History And Hepatitis B Or C Markers 70-Fold Elevated Risk Of Hepatocellular Carcinoma In Those With Family History And Hepatitis B Or C Markers A family history of liver cancer is reported to increase risk of developing hepatocellular carcinomas (HCC), independent of hepatitis according to findings published in the May issue of Hepatology, a journal of the American Association for the Study of Liver[…]
  
  Created on: 26 Apr 2012 | 1:00 am
  
  26 Apr 2012 | 1:00 am
• Soy Protein Alleviates Symptoms Of Fatty Liver Disease In Obese Patients Soy Protein Alleviates Symptoms Of Fatty Liver Disease In Obese Patients University of Illinois researchers report that new research shows how soy protein could significantly reduce fat accumulation and triglycerides in the livers of obese patients by partially restoring the function of a key signaling pathway in the organ...
  
  Created on: 24 Apr 2012 | 12:00 am
  
  24 Apr 2012 | 12:00 am
• Risk And Severity Of Liver Disease Reduced By Modest Alcohol Consumption Risk And Severity Of Liver Disease Reduced By Modest Alcohol Consumption People with nonalcoholic fatty liver disease (NALFD) who consume alcohol in modest amounts - no more than one or two servings per day - are half as likely to develop hepatitis as non-drinkers with the same condition, reports a national[…]
  
  Created on: 23 Apr 2012 | 1:00 am
  
  23 Apr 2012 | 1:00 am
• Transplanting Gut Microbiota May Protect From Diabetes And Fatty Liver Disease Transplanting Gut Microbiota May Protect From Diabetes And Fatty Liver Disease An exciting presentation at the International Liver Congress (TM) 2012 has revealed that gut microbiota play a contributing role in the development of diabetes and non-alcoholic fatty liver disease (NAFLD) independent of obesity. The French researchers underline that gut microbiota[…]
  
  Created on: 20 Apr 2012 | 12:00 pm
  
  20 Apr 2012 | 12:00 pm
• 82% Hepatitis C Cure Rate Achieved In Large Trial 82% Hepatitis C Cure Rate Achieved In Large Trial Up to 82% of patients with hepatitis C achieved viral cure after 28 weeks' treatment with a combination of Boehringer Ingelheim's investigational antiviral agents - the protease inhibitor BI 201335 and the polymerase inhibitor BI 207127, according to results from[…]
  
  Created on: 20 Apr 2012 | 9:00 am
  
  20 Apr 2012 | 9:00 am
• Recapitulation Of The Entire Hepatitis C Virus Life In Engineered Mouse Cell Lines Recapitulation Of The Entire Hepatitis C Virus Life In Engineered Mouse Cell Lines A US study presentedat The International Liver CongressTM 2012 demonstrates that the entire HCV lifecycle can be recapitulated in murine cells, implying that HCV permissive mouse models could soon be developed.(1) The data suggests that HCV replication in the murine[…]
  
  Created on: 20 Apr 2012 | 1:00 am
  
  20 Apr 2012 | 1:00 am

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